Evolution of Neurotransmitter-Related Genes in Primates
نویسندگان
چکیده
منابع مشابه
Mutations in human monoamine-related neurotransmitter pathway genes.
Biosynthesis and metabolism of serotonin and catecholamines involve at least eight individual enzymes that are mainly expressed in tissues derived from the neuroectoderm, e.g., the central nervous system (CNS), pineal gland, adrenal medulla, enterochromaffin tissue, sympathetic nerves, and ganglia. Some of the enzymes appear to have additional biological functions and are also expressed in the ...
متن کاملMolecular evolution of key receptor genes in primates and non-human primates
African primates remain an unexplored source of information required to complete the origin and evolution of many human pathogens. Current studies have shown the importance of several receptor human genes implicated in host resistance or susceptibility to tuberculosis. The validation of these genes in Mycobacterium tuberculosis infection makes them an excellent model system to investigate the m...
متن کاملAdaptive Evolution of Four Microcephaly Genes and the Evolution of Brain Size in Anthropoid Primates Authors:
The anatomical basis and adaptive function of the expansion in primate brain size have long been studied; however we are only beginning to understand the genetic basis of these evolutionary changes. Genes linked to human primary microcephaly have received much attention as they have accelerated evolutionary rates along lineages leading to humans. However these studies focus narrowly on apes and...
متن کاملAdaptive evolution of four microcephaly genes and the evolution of brain size in anthropoid primates.
The anatomical basis and adaptive function of the expansion in primate brain size have long been studied; however, we are only beginning to understand the genetic basis of these evolutionary changes. Genes linked to human primary microcephaly have received much attention as they have accelerated evolutionary rates along lineages leading to humans. However, these studies focus narrowly on apes, ...
متن کاملEvolution of microRNA in primates
MicroRNA play an important role in post-transcriptional regulation of most transcripts in the human genome, but their evolution across the primate lineage is largely uncharacterized. A particular miRNA can have one to thousands of messenger RNA targets, establishing the potential for a small change in sequence or overall miRNA structure to have profound phenotypic effects. However, the majority...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Primate Research
سال: 2000
ISSN: 1880-2117,0912-4047
DOI: 10.2354/psj.16.69